Uterine Cancer: Mutations Associated With Cancer Found in Endometriosis by 30Seconds Health

Women's Health Cancer
a year ago
Uterine Cancer: Mutations Associated With Cancer Found in Endometriosis

A study out in the New England Journal of Medicine is linking endometriosis with cancer. Findings from the study have identified cancer-related mutations in tissue taken from patients with deep infiltrating endometriosis (DIE), a non-cancerous tissue.

The joint study between Johns Hopkins University, Maryland, and the University of British Columbia, analyzed DIE lesions from a combined 27 patients from both New York City and Japan. Researchers sequenced the exome of healthy tissue and endometriosis tissue and found in 19 out of 24 samples one or more mutations in the endometriosis tissue that were not present in the corresponding normal tissue of the same patients. Researchers concluded that DIE lesions, which virtually have no risk of malignant transformation, do contain somatic cancer driver mutations, which are in fact operators for cell growth and survival.

"The study proved what I have long suspected,” said Dr. Tamer Seckin founder of the Seckin Endometriosis Center and the Endometriosis Foundation of America (EFA). "This is the first time that it has been demonstrated in a benign tissue that these cancer driver genes co-exist. In the past, we only identified mutations in cancer tissue. This study is the first time we see mutation sites in non-cancerous tissue.” He says the study will open doors to further studies to confirm similar or more definitive findings and that there may be markers that are unique to cancer-developing attributes to some endometriosis cases.

For more information on the study visit endofound.org and endonews.com.  

The information on 30Seconds.com is for informational and entertainment purposes only, and should not be considered medical advice. The information provided through this site should not be used to diagnose or treat a health problem or disease, and is not a substitute for professional care. Always consult your personal health care provider.

Elisa All Schmitz 30Seconds
So scary, but very important to know!

join discussion

Please login to comment.

recommended tips

Endometriosis Misdiagnosis: 9 Things Women Are Often Diagnosed With Instead!

Fighting Cancer: 3 Ways to Battle Loneliness During Cancer Treatment

Sleep Your Way to Good Health: 3 Tips to Get the Zzzz's You Need!

Do You Need Sunscreen in the Winter? For Your Skin's Sake, Read This!

Got 30 seconds? Sign up for 30Seconds.com and get the best of our tips each week!